Title list by research areas [Research Profiles 2026]
Life science
- Alternative splicing of Mff regulates AMPK-mediated phosphorylation, mitochondrial fission and antiviral response (Department of Biological Sciences, Graduate School of Science, Professor Naotada Ishihara)
- Harnessing free sulfate groups in glycosylation reactions (Department of Chemistry, Graduate School of Science, Professor Yasuhiro Kajihara; Assistant Professor Yuta Maki)
- Synthesis of polysaccharide derivatives forming narrow size-distribution flower micelles and structural analysis in aqueous solution (Department of Macromolecular Science, Graduate School of Science, Professor Ken Terao)
- Screening of nucleic acid-binding proteins based on profiling of molecular fingerprints (Division of Chemistry, Graduate School of Engineering Science, Associate Professor Junpei Yamamoto)
- AI ultrasonic microscope for long-term, high-resolution observation of living cells (Department of Precision Science & Technology, Graduate School of Engineering, Professor Hirotsugu Ogi)
- Cationic polymer effect on brown adipogenic induction of dedifferentiated fat cells (Department of Applied Chemistry, Graduate School of Engineering, Postdoctoral Researcher Asli Sena Karanfil; Joint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry, Graduate School of Engineering, Specially Appointed Assistant Professor Fiona Louis)
- Development of a multicolor bioluminescence imaging method for simultaneous monitoring of multiple cellular activities (Department of Biomolecular Science and Engineering, SANKEN (The Institute of Scientific and Industrial Research), Associate Professor Mitsuru Hattori; Professor Takeharu Nagai)
- Novel CAR T cells and cord blood-derived CAR NK cells for relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation (Department of Hematology and Oncology, Graduate School of Medicine, Professor Naoki Hosen)
- A multivariate model incorporating subharmonic measurements for evaluating vocal roughness (Department of Otorhinolaryngology–Head and Neck Surgery, Graduate School of Medicine, Visiting Academic Staff Itsuki Kitayama; Associate Professor (Lecturer) Kiyohito Hosokawa; Professor Hidenori Inohara)
- Restoring autophagy to protect the kidney: A novel mechanism of SGLT2 inhibitors (Department of Nephrology, Graduate School of Medicine, Specially Appointed Assistant Professor Takeshi Yamamoto; Professor Yoshitaka Isaka)
- Effective transcatheter intracoronary delivery of mRNA-lipid nanoparticles targeting the heart (Department of Cardiovascular Surgery, Graduate School of Medicine, Ph.D Student Kazuma Handa; Guest Associate Professor Masashi Kawamura; Professor Shigeru Miyagawa)
- Framework for predicting the risk of severe sports injuries: Toward an integrative understanding of athlete psychology and cognitive biomechanics (Department of Health and Sport Sciences, Graduate School of Medicine, Associate Professor Issei Ogasawara)
- Development of a secretin-stimulated, catheter-assisted method for the early detection of pancreatic cancer during esophagogastroduodenoscopy (Department of Cancer Genome Informatics, Graduate School of Medicine, Professor Shinichi Yachida)
- Nanoclay gel as a next-generation BMP carrier: Minimizing adverse events and promoting high-quality bone regeneration (Orthopedic Surgery, Graduate School of Medicine, Specially Appointed Associate Professor Takashi Kaito; Professor Seiji Okada)
- A Vaccine against FAP (fibroblast activation protein) improves murine cardiac fibrosis by preventing the accumulation of myofibroblasts (Department of Health Development and Medicine, Graduate School of Medicine, Endowed Chair Professor Hironori Nakagami; Endowed Chair Associate Professor Hiroki Hayashi)
- A novel therapeutic strategy for photoimmunotherapy via intratumoral delivery of antibody–photoabsorber conjugates (Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Visiting Academic Staff Yuichi Adachi; Assistant Professor Kotaro Miyake)
- Amygdalar Semaphorin signaling integrates emotional, metabolic, and hematopoietic responses (Immune Regulation laboratory, Immunology Frontier Research Center, Endowed Research Department Associate Professor Sujin Kang; Department of Advanced Clinical and Translational Immunology, Graduate School of Medicine, Specially Appointed Assistant Professor Yoshimitsu Nakanishi; Specially Appointed Assistant Professor Mayuko Izumi)
- GDF15 propeptide promotes bone metastasis of castration-resistant prostate cancer by augmenting the bone microenvironment (Department of Urology, Graduate School of Medicine, Attending Staff (Physician) Gaku Yamamichi; Associate Professor (Lecturer) Taigo Kato; Professor Norio Nonomura)
- Combination of pimitespib with sunitinib is an effective therapy for imatinib-resistant gastrointestinal stromal tumors (Department of Gastroenterological Surgery, Graduate School of Medicine, Associate Professor (Lecturer) Tsuyoshi Takahashi; Department of Gastroenterological Surgery, Graduate School of Medicine (Current affiliation: Kindai University Nara Hospital), Ph.D. Student (Current Job title: Assistant Professor) Ryugo Teranishi; Department of Gastroenterological Surgery, Graduate School of Medicine, Professor Yuichiro Doki)
- Mechanism of autophagy initiation by palmitoylation (Department of Genetics, Graduate School of Medicine/Graduate School of Frontier Biosciences, Associate Professor Maho Hamasaki)
- Enantiodivergent synthesis of chiral compounds using a single enzyme (Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Assistant Professor Kyohei Kanomata)
- Platform using human iPS cell-derived hepatic organoids for pharmaceutical research (Graduate School of Pharmaceutical Sciences, Laboratory of Biochemistry and Molecular Biology, Professor Hiroyuki Mizuguchi)
- Identification of cancer-specific RNA modifications in extracellular vesicles and their pathological significance (Laboratory of Stem Cell Regeneration and Adaptation, Graduate School of Pharmaceutical Sciences, Associate Professor (Lecturer) Kentaro Jingushi)
- Low-inflammatory lipid nanoparticle-based mRNA vaccine elicits protective immunity against H5N1 high-pathogenicity avian influenza virus with reduced adverse reactions (Vaccine Creation Group, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Specially Appointed Professor Yasuo Yoshioka)
- Liver defender macrophages: A novel discovery with therapeutic potential (Department of Immunology and Cell Biology, Graduate School of Frontier Biosciences, Assistant Professor Yu Miyamoto; Department of Immunology and Cell Biology, Graduate School of Medicine, Professor Masaru Ishii)
- Identification of Ras activators (RasGEFs) triggering cellular amoeboid movement (Laboratory of Single Molecule Biology, Graduate School of Frontier Biosciences, Assistant Professor Satomi Matsuoka; Professor Masahiro Ueda)
- High-throughput single-molecule tracking technology streamlines drug discovery (Laboratory of Single Molecule Biology, Graduate School of Frontier Biosciences, Professor Masahiro Ueda; Specially Appointed Professor Michio Hiroshima)
- A cell-cell communication system which enables highly reproducible construction of healthy body (Department of Homeostatic Regulation, Research Institute for Microbial Diseases, Professor Tohru Ishitani)
- What’s your body really worth? New AI model reveals your true biological age from 5 drops of blood (Laboratory for Computational Biology, Institute for Protein Research, Specially Appointed Assistant Professor Zi Wang; Laboratory of Protein Organic Chemistry, Institute for Protein Research, Specially Appointed Professor (Professor Emeritus) Toshifumi Takao)
- Epigenome-driven adaptation of Staphylococcus aureus and regulatory control of virulence in hospital environments (Cutaneous Allergy and Host Defense, Immunology Frontier Research Center, Professor Yumi Matsuoka (Yuumi Nakamura))
- Regulation of Treg cell functional stability by the Foxp3-Ikzf1 complex (Laboratory of Experimental Immunology, Immunology Frontier Research Center, Specially Appointed Associate Professor Kenji Ichiyama)
- Self-generated intracellular heat drives neuronal differentiation (Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Specially Appointed Professor Yoshie Harada)
- Targeting fibroblast diversity as a new avenue for cancer therapy (Center for Infectious Disease Education and Research, Specially Appointed Assistant Professor Akikazu Harada; Specially Appointed Professor Akira Kikuchi)
- New methods for understanding human regulatory T cell functions (Human Single Cell Immunology Team, Division of Microbiology and Immunology, Center for Infectious Disease Education and Research (CiDER), Professor James Badger Wing)
- Mechanisms and biological significance of plasma cell migration to the bone marrow (Regulation of Host Defense Team, Center for Infectious Disease Education and Research, Professor Wataru Ise)
- Elucidating the origins of homeostatic systems: developmental transition from morphogenesis to tissue homeostasis (Graduate School of Frontier Biosciences, Associate Professor Ritsuko Morita)
- Deciphering disease biology through energy metabolism: A novel approach focusing on hyaluronan (Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry/Department of Orthodontics, The University of Osaka Dental Hospital, Associate Professor Toshihiro Inubushi)
- Development of ploidy diagnostic technologies to achieve personalized medicine for refractory cancers (Laboratory of Ploidy Pathology, Graduate School of Frontier Biosciences, Associate Professor Tomonori Matsumoto)
- Visualizing and interpreting the dynamics of life-related crystals (Division of Electrical, Electronic and Infocommunications Engineering, Graduate School of Engineering, Professor Mihoko Maruyama; Assistant Professor Hozumi Takahashi; Specially Appointed Assistant Professor Yutaro Tanaka)
Telecommunications
- Signal processing design for enabling massive wireless connectivity (Division of Electrical, Electronic and Infocommunications Engineering, Graduate School of Engineering, Associate Professor Takumi Takahashi)
- Uncertainty-exploiting energy-efficient AI Control: integrating event-triggered control with probabilistic inference (Division of Electrical, Electronic and Infocommunications Engineering, Graduate School of Engineering, Associate Professor Kazumune Hashimoto)
- Development of a new control algorithm that enables cyborg insects to move as a swarm (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Professor Naoki Wakamiya)
- LLM-based urban transportation simulation framework (Department of Information Networking, Graduate School of Information Science and Technology, Assistant Professor Tatsuya Amano)
- Dialogue agents mediating diverse social relationships based on values models (Department of System Innovation, Graduate School of Engineering Science, Assistant Professor Takahisa Uchida)
- Information flow in turbulence (Department of Earth and Space Science, Graduate School of Science, Assistant Professor Tomohiro Tanogami)
- Developing learning theory for uncertainty using Information theory (Department of Systems Innovation, Graduate School of Engineering science, Associate Professor Futoshi Futami)
Nanotechnologies / Materials
- Sustainable polymer materials: Controlled degradation and re-construction technologies (Department of Macromolecular Science, Graduate School of Science, Professor Yoshinori Takashima)
- Design and synthesis of metastable strongly correlated materials using first-principles calculations (Department of Materials Engineering Science, Graduate School of Engineering Science, Professor Shintaro Ishiwata)
- Development of diradical molecules exhibiting spin-correlated luminescence (Department of Materials Engineering Science, Graduate School of Engineering Science, Assistant Professor Asato Mizuno)
- Beyond precious metals: Redefining catalysis with ubiquitous metals (Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Takato Mitsudome)
- Quantitative atomistic simulation of structural materials using machine‑learning interatomic potentials (Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Professor Shigenobu Ogata; Assistant Professor Shuhei Shinzato)
- Plasmon–molecule remote coupling for enhanced optical spectroscopy (Department of Systems Innovation, Graduate School of Engineering Science, Professor Takeo Minamikawa)
- Control of interlayer interactions in multilayer graphene via nanodiamond insertion (Department of Applied Physics, Graduate School of Engineering, Ph.D Student Mingda Ding; Assistant Professor Taiki Inoue; Professor Yoshihiro Kobayashi)
- Transition-metal-free arylamine synthesis utilizing hypervarent iodines (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Kensuke Kiyokawa)
- Development of chemically synthesized boron monolayer (chemical borophene) (Center for Future Innovation, Graduate School of Engineering, Associate Professor Tetsuya Kambe)
- Aryne polymerization by organonucleophile (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Hayato Fujimoto; Professor Mamoru Tobisu)
- Short-step synthesis of cyclopentadiene derivatives catalyzed by niobium complexes (Department of Applied Chemistry, Graduate School of Engineering, Professor Hayato Tsurugi)
- High-performance sequence-controlled PLA bioplastics with adjustable marine biodegradability (Division of Applied Chemistry, Graduate School of Engineering, Associate Professor Yu-I Hsu)
- Synthesis and characterization of a novel polycyclic hydrocarbon containing a planar octagon (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Akihito Konishi; Professor Makoto Yasuda; Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Ryohei Kishi)
- Quick and scalable synthesis of carborane-substituted arenes via a dump-and-stir cuprate reagent: Unlocking applications in BNCT, drug design, and functional materials (Center for Future Innovation, Graduate School of Engineering, TechnoArena Professor Yoichi Hoshimoto)
- Technology for immobilizing noble metal nanoparticles on various substrates (Department of Management of Industry and Technology, Graduate School of Engineering, Associate Professor Satoshi Seino)
- Development of organic semiconductor materials with small exciton binding energies toward photoelectric conversion applications (Department of Soft Nanomaterials, SANKEN (The Institute of Scientific and Industrial Research), Assistant Professor Seihou Jinnai; Professor Yutaka Ie)
- Realization of high-efficiency hopping conduction in several-nanometer-scale molecular wires (Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Ryo Yamada; Department of Soft Nanomaterials, SANKEN (The Institute of Scientific and Industrial Research), Professor Yutaka Ie)
- Solid-state nanopore sequencing (Department of Bio-Nanotechnology, SANKEN (The Institute of Scientific and Industrial Research), Associate Professor Makusu Tsutsui)
- New developments in quantum many-body systems through the integration of quasicrystal property research and quantum algorithm development (Department of Physics, Graduate School of Science, Associate Professor Nayuta Takemori)
Energy
Manufacturing technologies
- Construction of artificial metalloenzymes for challenging chemical transformations (Department of Applied Chemistry, Graduate School of Engineering, Associate Professor Koji Oohora)
- Positive oxygen enabled by designed peroxides (Department of Applied Chemistry, Graduate School of Engineering, Professor Koji Hirano)
- A new strategy for PFAS decomposition and transformation using photocatalysis and Lewis acid activation (Department of Applied Chemistry, Graduate School of Engineering, Associate Professor Yoshihiro Nishimoto; Professor Makoto Yasuda)
- Development of a low-temperature methanation self-catalytic reactor using a metal 3D printer (Division of Materials and Manufacturing Science, Graduate School of Engineering, Professor Kohsuke Mori; Specially Appointed Assistant Professor Hyo-Jin Kim)
- Technology assessment and design of new directions of innovation by adopting “Imaginary Future Generations” – a case study of hydrothermal technology (Center for Future Innovation, Graduate School of Engineering, Professor Keishiro Hara; Headquarter, Executive Vice President Toshihiro Tanaka; Division of Materials and Manufacturing Science, Graduate School of Engineering, Associate Professor Masanori Suzuki)
- Development of cold spot joining method for high strength and lightweight metal structures (Joining and welding research institute, Specially Appointed Associate Professor Yoshiaki Morisada; Professor Hidetoshi Fujii)
- Investigation of structure formation mechanisms by materials and fluid interaction (Department of Mechanical Engineering, Graduate School of Engineering, Associate Professor (Lecturer) Takahiro Suzuki)
- Investigation of color centers in silicon carbide for quantum technology applications (Division of Precision Engineering and Applied Physics, Graduate School of Engineering, Associate Professor Takuma Kobayashi)
Social innovation
- Building responsible research and innovation through Ethics by Design and ELSI education (Center for the Study of CO* Design / Research center on Ethical, Legal and Social Issues, Specially Appointed Associate Professor (Lecturer) Yusuke Shikano)
- Research project to support “family formation” for people with mental illnesses (Institute for Advanced Co-Creation Studies, Professor Masako Kageyama)
- Estimation of topics and social influences on social media contents (Department of Management, Graduate School of Economics, Associate Professor Mirai Igarashi)
- Re-examining educational policies for foreigners and immigrants from an institutional perspective (Department of Human Sciences, Graduate School of Human Sciences, Professor Daisuke Sonoyama)
- Menstrual well-being by and in social design (Global Studies, Kyosei Studies, Graduate School of Human Sciences, Professor Elli Sugita)
- Understanding of the feeling of “kawaii” and its real-world applications (Department of General Psychology, Graduate School of Human Sciences, Professor Hiroshi Nittono)
- Toward an integration of law and psychology (Department of Social Psychology, Graduate School of Human Sciences, Professor Eiichiro Watamura)
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